SF3A3（splicing factor 3a subunit 3），癌症关联基因，基因ID：10946，该基因编码剪接因子3a蛋白复合物的亚基3剪接因子3A异源三聚体包括亚单位1、2和3，并且是将15S U2 SNRNP体外转化为进行前mRNA剪接的活性17S粒子所必需的。亚基3通过其氨基末端与亚基1相互作用，而亚基3的锌指结构域在其与15s u2 snrnp的结合中起作用。这个基因在20号染色体上有一个假基因。选择性剪接导致多个转录变体[由RefSeq提供，2016年3月]This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1， 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq， Mar 2016]。